Reaction Details Report a problem with these data
Target
Bifunctional epoxide hydrolase 2
Ligand
BDBM41929
Substrate
n/a
Meas. Tech.
sEH_DR_Inh_Infinite200_Fluorescence_01072008
IC50
22.2±n/a nM
Citation
 PubChem, PC sEH_DR_Inh_Infinite200_Fluorescence_01072008 PubChem Bioassay (2008)[AID] 
Target
Name:
Bifunctional epoxide hydrolase 2
Synonyms:
Cytosolic epoxide hydrolase 2 | EBifunctional epoxide hydrolase 2 | EPHX2 | Epoxide hydratase | HYES_HUMAN | Lipid-phosphate phosphatase | Soluble epoxide hydrolase (sEH) | epoxide hydrolase 2, cytoplasmic
Type:
Enzyme
Mol. Mass.:
62613.07
Organism:
Homo sapiens (Human)
Description:
P34913
Residue:
555
Sequence:
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM
  
Inhibitor
Name:
BDBM41929
Synonyms:
MLS000565972 | N'-[(Z)-(4-chloranyl-2-phenylimino-1,3-thiazol-5-ylidene)methyl]-2-(4-cyanophenoxy)ethanehydrazide | N'-[(Z)-(4-chloro-2-phenylimino-1,3-thiazol-5-ylidene)methyl]-2-(4-cyanophenoxy)acetohydrazide | N'-[(Z)-(4-chloro-2-phenylimino-3-thiazolin-5-ylidene)methyl]-2-(4-cyanophenoxy)acetohydrazide | N'-[(Z)-(4-chloro-2-phenylimino-5-thiazolylidene)methyl]-2-(4-cyanophenoxy)acetohydrazide | SMR000153121 | cid_6507285
Type:
Small organic molecule
Emp. Form.:
C19H14ClN5O2S
Mol. Mass.:
411.865
SMILES:
Clc1nc(Nc2ccccc2)sc1C=NNC(=O)COc1ccc(cc1)C#N |w:14.16|
Structure:
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