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Target
Dual specificity protein phosphatase 6
Ligand
BDBM31765
Substrate
n/a
Meas. Tech.
MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors
IC50
15300±500 nM
Citation
 PubChem, PC MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors PubChem Bioassay (2008)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM31765
Synonyms:
MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-thiophen-2-yl-ethanamide | N-(5-methyl-1,2-oxazol-3-yl)-2-thiophen-2-ylacetamide | N-(5-methyl-3-isoxazolyl)-2-thiophen-2-ylacetamide | N-(5-methylisoxazol-3-yl)-2-(2-thienyl)acetamide | cid_717599
Type:
Small organic molecule
Emp. Form.:
C10H10N2O2S
Mol. Mass.:
222.264
SMILES:
Cc1cc(NC(=O)Cc2cccs2)no1
Structure:
Search PDB for entries with ligand similarity: