Reaction Details Report a problem with these data
Target
Estrogen receptor
Ligand
BDBM40990
Substrate
n/a
Meas. Tech.
Estrogen Receptor (alpha) binding: Dose Response of Primary Screen Assay
EC50
>10000±n/a nM
Citation
 PubChem, PC Estrogen Receptor (alpha) binding: Dose Response of Primary Screen Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Estrogen receptor
Synonyms:
ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1
Type:
Protein
Mol. Mass.:
66230.44
Organism:
Homo sapiens (Human)
Description:
P03372
Residue:
595
Sequence:
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
  
Inhibitor
Name:
BDBM40990
Synonyms:
2-(3,5-dimethylphenoxy)-N-(4-pyrrolidin-1-ylphenyl)acetamide | 2-(3,5-dimethylphenoxy)-N-(4-pyrrolidin-1-ylphenyl)ethanamide | 2-(3,5-dimethylphenoxy)-N-(4-pyrrolidinophenyl)acetamide | 2-(3,5-dimethylphenoxy)-N-[4-(1-pyrrolidinyl)phenyl]acetamide | MLS000112626 | SMR000108537 | cid_960705
Type:
Small organic molecule
Emp. Form.:
C20H24N2O2
Mol. Mass.:
324.4168
SMILES:
Cc1cc(C)cc(OCC(=O)Nc2ccc(cc2)N2CCCC2)c1
Structure:
Search PDB for entries with ligand similarity: