Reaction Details Report a problem with these data
Target
Glyceraldehyde-3-phosphate dehydrogenase
Ligand
BDBM41877
Substrate
n/a
Meas. Tech.
GAPDH Dose Response Colorimetric Assay
IC50
5300±270 nM
Citation
 PubChem, PC GAPDH Dose Response Colorimetric Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Glyceraldehyde-3-phosphate dehydrogenase
Synonyms:
G3P_HUMAN | GAPD | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase liver
Type:
PROTEIN
Mol. Mass.:
36060.86
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1511315
Residue:
335
Sequence:
MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE
  
Inhibitor
Name:
BDBM41877
Synonyms:
4,5,6,7-tetrachloro-2-(1H-1,2,4-triazol-5-yl)isoindole-1,3-dione | 4,5,6,7-tetrachloro-2-(1H-1,2,4-triazol-5-yl)isoindoline-1,3-quinone | 4,5,6,7-tetrakis(chloranyl)-2-(1H-1,2,4-triazol-5-yl)isoindole-1,3-dione | MLS-0146264.0001 | cid_2975202
Type:
Small organic molecule
Emp. Form.:
C10H2Cl4N4O2
Mol. Mass.:
351.96
SMILES:
Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1nnc[nH]1
Structure:
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