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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42227
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
48568.40515±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42227
Synonyms:
2-(2-Methoxy-phenylamino)-3-piperidin-1-yl-[1,4]naphthoquinone | 2-(2-methoxyanilino)-3-(1-piperidinyl)naphthalene-1,4-dione | 2-(2-methoxyanilino)-3-piperidin-1-ylnaphthalene-1,4-dione | 2-(o-anisidino)-3-piperidino-1,4-naphthoquinone | 2-[(2-methoxyphenyl)amino]-3-piperidin-1-yl-naphthalene-1,4-dione | MLS000590461 | SMR000217508 | cid_1388836
Type:
Small organic molecule
Emp. Form.:
C22H22N2O3
Mol. Mass.:
362.4217
SMILES:
COc1ccccc1NC1=C(N2CCCCC2)C(=O)c2ccccc2C1=O |c:10|
Structure:
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