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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42253
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42253
Synonyms:
2-(2-hydroxyethylamino)-3-(4-methoxyanilino)naphthalene-1,4-dione | 2-(2-hydroxyethylamino)-3-(p-anisidino)-1,4-naphthoquinone | 2-(2-hydroxyethylamino)-3-[(4-methoxyphenyl)amino]naphthalene-1,4-dione | 2-[(2-hydroxyethyl)amino]-3-[(4-methoxyphenyl)amino]naphthoquinone | MLS000665375 | SMR000270476 | cid_2914402
Type:
Small organic molecule
Emp. Form.:
C19H18N2O4
Mol. Mass.:
338.3572
SMILES:
COc1ccc(Nc2c(O)c3ccccc3c(O)c2NCC=O)cc1
Structure:
Search PDB for entries with ligand similarity: