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Target
Mitogen-activated protein kinase 10
Ligand
BDBM37414
Substrate
n/a
Meas. Tech.
Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3)
IC50
64310±n/a nM
Citation
 PubChem, PC Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3) PubChem Bioassay (2008)[AID] 
Target
Name:
Mitogen-activated protein kinase 10
Synonyms:
JNK3 | JNK3A | MAP kinase p49 3F12 | MAPK10 | MK10_HUMAN | Mitogen-Activated Protein Kinase 10 (JNK3) | Mitogen-activated protein kinase 10 (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) | Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 | PRKM10 | SAPK1B | Stress-activated protein kinase JNK3 | c-Jun N-terminal kinase 3 (JNK3)
Type:
Enzyme
Mol. Mass.:
52586.89
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
464
Sequence:
MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
  
Inhibitor
Name:
BDBM37414
Synonyms:
MLS000095297 | N-cyclopentyl-4-(4-keto-2-thioxo-1H-quinazolin-3-yl)butyramide | N-cyclopentyl-4-(4-oxidanylidene-2-sulfanylidene-1H-quinazolin-3-yl)butanamide | N-cyclopentyl-4-(4-oxo-2-sulfanylidene-1H-quinazolin-3-yl)butanamide | N-cyclopentyl-4-(4-oxo-2-thioxo-1,4-dihydroquinazolin-3(2H)-yl)butanamide | SMR000030851 | cid_3241597
Type:
Small organic molecule
Emp. Form.:
C17H21N3O2S
Mol. Mass.:
331.433
SMILES:
O=C(CCCn1c(=S)[nH]c2ccccc2c1=O)NC1CCCC1
Structure:
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