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Target
Cell division control protein 42 homolog
Ligand
BDBM43209
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
EC50
15440±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
G25K GTP-binding protein | CDC42_HUMAN | CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | Cell division control protein 42 homolog
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Human
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM43209
Synonyms:
MLS000537345 | 1-(3-methoxyphenyl)-5-methylsulfonyltetrazole | 1-(3-methoxyphenyl)-5-(methylsulfonyl)-1H-tetrazole | 1-(3-methoxyphenyl)-5-methylsulfonyl-1,2,3,4-tetrazole | SMR000143783 | cid_2221997 | 5-mesyl-1-(3-methoxyphenyl)tetrazole
Type:
Small organic molecule
Emp. Form.:
C9H10N4O3S
Mol. Mass.:
254.05
SMILES:
COc1cccc(c1)-n1nnnc1S(C)(=O)=O
Structure:
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