Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43233
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant
EC50
21710±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43233
Synonyms:
1-benzyl-5-chloro-3-methyl-pyrazole-4-carboxylic acid | 1-benzyl-5-chloro-3-methylpyrazole-4-carboxylic acid | 5-chloranyl-3-methyl-1-(phenylmethyl)pyrazole-4-carboxylic acid | 5-chloro-3-methyl-1-(phenylmethyl)-4-pyrazolecarboxylic acid | MLS000759940 | SMR000370104 | cid_2393574
Type:
Small organic molecule
Emp. Form.:
C12H11ClN2O2
Mol. Mass.:
250.681
SMILES:
Cc1nn(Cc2ccccc2)c(Cl)c1C(O)=O
Structure:
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