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Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43287
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant
EC50
65060±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43287
Synonyms:
4,4-dimethyl-1-(4-nitrophenyl)-2-pentyn-1-one | 4,4-dimethyl-1-(4-nitrophenyl)pent-2-yn-1-one | UNM000011085701 | cid_25109923
Type:
Small organic molecule
Emp. Form.:
C13H13NO3
Mol. Mass.:
231.2472
SMILES:
CC(C)(C)C#CC(=O)c1ccc(cc1)[N+]([O-])=O
Structure:
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