Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM41646
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
4978±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM41646
Synonyms:
MLS000098950 | N-(1H-benzimidazol-2-yl)-2-(1H-indol-3-yl)acetamide | N-(1H-benzimidazol-2-yl)-2-(1H-indol-3-yl)ethanamide | SMR000063853 | cid_2125826
Type:
Small organic molecule
Emp. Form.:
C17H14N4O
Mol. Mass.:
290.3193
SMILES:
O=C(Cc1c[nH]c2ccccc12)Nc1nc2ccccc2[nH]1
Structure:
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