Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43566
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
2025±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43566
Synonyms:
6-[1-(2-methoxyanilino)-1-oxobutan-2-yl]-5-thieno[2,3-b]pyrrolecarboxylic acid methyl ester | 6-[1-[(2-methoxyphenyl)carbamoyl]propyl]thieno[2,3-b]pyrrole-5-carboxylic acid methyl ester | MLS000093503 | SMR000029121 | cid_3240686 | methyl 6-(1-{[(2-methoxyphenyl)amino]carbonyl}propyl)-6H-thieno[2,3-b]pyrrole-5-carboxylate | methyl 6-[1-(2-methoxyanilino)-1-oxobutan-2-yl]thieno[2,3-b]pyrrole-5-carboxylate | methyl 6-[1-[(2-methoxyphenyl)amino]-1-oxidanylidene-butan-2-yl]thieno[2,3-b]pyrrole-5-carboxylate
Type:
Small organic molecule
Emp. Form.:
C19H20N2O4S
Mol. Mass.:
372.438
SMILES:
CCC(C(=O)Nc1ccccc1OC)n1c(cc2ccsc12)C(=O)OC
Structure:
Search PDB for entries with ligand similarity: