Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43569
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
1711±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43569
Synonyms:
MLS000087216 | N-(4-chloranyl-2,5-dimethoxy-phenyl)-5-(furan-2-yl)-1,2-oxazole-3-carboxamide | N-(4-chloro-2,5-dimethoxy-phenyl)-5-(2-furyl)isoxazole-3-carboxamide | N-(4-chloro-2,5-dimethoxyphenyl)-5-(2-furanyl)-3-isoxazolecarboxamide | N-(4-chloro-2,5-dimethoxyphenyl)-5-(2-furyl)isoxazole-3-carboxamide | N-(4-chloro-2,5-dimethoxyphenyl)-5-(furan-2-yl)-1,2-oxazole-3-carboxamide | SMR000023439 | cid_3243301
Type:
Small organic molecule
Emp. Form.:
C16H13ClN2O5
Mol. Mass.:
348.738
SMILES:
COc1cc(NC(=O)c2cc(on2)-c2ccco2)c(OC)cc1Cl
Structure:
Search PDB for entries with ligand similarity: