Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43571
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
5795±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43571
Synonyms:
2-(4-methoxyphenyl)-6-phenyl-[1,3]thiazolo[3,2-b][1,2,4]triazole | 2-(4-methoxyphenyl)-6-phenyl-thiazolo[3,2-b][1,2,4]triazole | 2-(4-methoxyphenyl)-6-phenyl[1,3]thiazolo[3,2-b][1,2,4]triazole | 2-(4-methoxyphenyl)-6-phenylthiazolo[3,2-b][1,2,4]triazole | MLS000049582 | SMR000076125 | cid_2140141
Type:
Small organic molecule
Emp. Form.:
C17H13N3OS
Mol. Mass.:
307.37
SMILES:
COc1ccc(cc1)-c1nc2scc(-c3ccccc3)n2n1
Structure:
Search PDB for entries with ligand similarity: