Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43585
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
3777±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43585
Synonyms:
3-(4-chlorophenyl)-1-methyl-N-[3-(4-methyl-1-piperazinyl)propyl]-5-thieno[2,3-c]pyrazolecarboxamide | 3-(4-chlorophenyl)-1-methyl-N-[3-(4-methylpiperazin-1-yl)propyl]thieno[2,3-c]pyrazole-5-carboxamide | 3-(4-chlorophenyl)-1-methyl-N-[3-(4-methylpiperazino)propyl]thieno[2,3-c]pyrazole-5-carboxamide | MLS000117299 | SMR000094249 | cid_5308230
Type:
Small organic molecule
Emp. Form.:
C21H26ClN5OS
Mol. Mass.:
431.982
SMILES:
CN1CCN(CCCNC(=O)c2cc3c(nn(C)c3s2)-c2ccc(Cl)cc2)CC1
Structure:
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