Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43595
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>76±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43595
Synonyms:
MLS000104263 | N-(1-acetyl-2-chloro-3-indolyl)acetamide | N-(1-acetyl-2-chloro-indol-3-yl)acetamide | N-(1-acetyl-2-chloroindol-3-yl)acetamide | N-(2-chloranyl-1-ethanoyl-indol-3-yl)ethanamide | SMR000054198 | cid_788168
Type:
Small organic molecule
Emp. Form.:
C12H11ClN2O2
Mol. Mass.:
250.681
SMILES:
CC(=O)Nc1c(Cl)n(C(C)=O)c2ccccc12
Structure:
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