Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43599
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>229±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43599
Synonyms:
MLS000520019 | N-(4-chloranyl-2,5-dimethoxy-phenyl)-5-propan-2-yl-1,2-oxazole-3-carboxamide | N-(4-chloro-2,5-dimethoxy-phenyl)-5-isopropyl-isoxazole-3-carboxamide | N-(4-chloro-2,5-dimethoxyphenyl)-5-propan-2-yl-1,2-oxazole-3-carboxamide | N-(4-chloro-2,5-dimethoxyphenyl)-5-propan-2-yl-3-isoxazolecarboxamide | SMR000130434 | cid_9550420
Type:
Small organic molecule
Emp. Form.:
C15H17ClN2O4
Mol. Mass.:
324.759
SMILES:
COc1cc(NC(=O)c2cc(on2)C(C)C)c(OC)cc1Cl
Structure:
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