Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43603
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
521±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43603
Synonyms:
5-(2-ethoxyphenyl)-1,3,4-oxadiazole-2-thiol | 5-(2-ethoxyphenyl)-3H-1,3,4-oxadiazole-2-thione | 5-o-phenetyl-3H-1,3,4-oxadiazole-2-thione | MLS000538614 | SMR000144651 | cid_2235547
Type:
Small organic molecule
Emp. Form.:
C10H10N2O2S
Mol. Mass.:
222.264
SMILES:
CCOc1ccccc1-c1nnc(S)o1
Structure:
Search PDB for entries with ligand similarity: