Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43625
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>2062±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43625
Synonyms:
1-(2-fluorophenyl)-2-[(4-methyl-1,2,5-oxadiazol-3-yl)acetyl]-2,3,4,9-tetrahydro-1H-beta-carboline | 1-[1-(2-fluorophenyl)-1,3,4,9-tetrahydro-beta-carbolin-2-yl]-2-(4-methylfurazan-3-yl)ethanone | 1-[1-(2-fluorophenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone | MLS000733583 | SMR000318043 | cid_16187888
Type:
Small organic molecule
Emp. Form.:
C22H19FN4O2
Mol. Mass.:
390.4103
SMILES:
Cc1nonc1CC(=O)N1CCc2c([nH]c3ccccc23)C1c1ccccc1F
Structure:
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