Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43634
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
1298±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43634
Synonyms:
2-methyl-N-[4-[(o-anisoylamino)carbamoyl]phenyl]propionamide | MLS000672334 | N-(4-{[2-(2-methoxybenzoyl)hydrazino]carbonyl}phenyl)-2-methylpropanamide | N-[4-[[(2-methoxybenzoyl)amino]carbamoyl]phenyl]-2-methylpropanamide | N-[4-[[(2-methoxyphenyl)carbonylamino]carbamoyl]phenyl]-2-methyl-propanamide | N-[4-[[[(2-methoxyphenyl)-oxomethyl]hydrazo]-oxomethyl]phenyl]-2-methylpropanamide | SMR000295764 | cid_1242183
Type:
Small organic molecule
Emp. Form.:
C19H21N3O4
Mol. Mass.:
355.3877
SMILES:
COc1ccccc1C(=O)NNC(=O)c1ccc(NC(=O)C(C)C)cc1
Structure:
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