Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43635
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
2847±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43635
Synonyms:
3-[5-(1,3-benzodioxol-5-ylmethyl)-1,3,4-oxadiazol-2-yl]-N-(1,3-benzothiazol-2-ylmethyl)propanamide | MLS000733493 | N-(1,3-benzothiazol-2-ylmethyl)-3-(5-piperonyl-1,3,4-oxadiazol-2-yl)propionamide | SMR000316923 | cid_16191260
Type:
Small organic molecule
Emp. Form.:
C21H18N4O4S
Mol. Mass.:
422.457
SMILES:
O=C(CCc1nnc(Cc2ccc3OCOc3c2)o1)NCc1nc2ccccc2s1
Structure:
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