Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43645
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
571±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43645
Synonyms:
MLS000621487 | N-(5-chloranyl-2-oxidanyl-phenyl)-2-(2-chloranylphenoxy)ethanamide | N-(5-chloro-2-hydroxy-phenyl)-2-(2-chlorophenoxy)acetamide | N-(5-chloro-2-hydroxyphenyl)-2-(2-chlorophenoxy)acetamide | SMR000299591 | cid_893676
Type:
Small organic molecule
Emp. Form.:
C14H11Cl2NO3
Mol. Mass.:
312.148
SMILES:
Oc1ccc(Cl)cc1NC(=O)COc1ccccc1Cl
Structure:
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