Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43655
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
635±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43655
Synonyms:
(3Z)-3-[(4-bromanylthiophen-2-yl)methylidene]-1-methyl-indol-2-one | (3Z)-3-[(4-bromo-2-thienyl)methylene]-1-methyl-oxindole | (3Z)-3-[(4-bromo-2-thiophenyl)methylidene]-1-methyl-2-indolone | (3Z)-3-[(4-bromothiophen-2-yl)methylidene]-1-methylindol-2-one | MLS000770538 | SMR000375862 | cid_2109452
Type:
Small organic molecule
Emp. Form.:
C14H10BrNOS
Mol. Mass.:
320.204
SMILES:
CN1C(=O)\C(=C/c2cc(Br)cs2)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: