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Target
G2/mitotic-specific cyclin-B1
Ligand
BDBM43760
Substrate
n/a
Meas. Tech.
Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation
EC50
>49750±n/a nM
Citation
 PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay (2008)[AID] 
Target
Name:
G2/mitotic-specific cyclin-B1
Synonyms:
CCNB | CCNB1 | CCNB1_HUMAN
Type:
Enzyme Subunit
Mol. Mass.:
48340.95
Organism:
Homo sapiens (Human)
Description:
P14635
Residue:
433
Sequence:
MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDLAKAVAKV
  
Inhibitor
Name:
BDBM43760
Synonyms:
MLS000565334 | N'-(5-bromanyl-2-oxidanylidene-indol-3-yl)-2-pyrrol-1-yl-benzohydrazide | N'-(5-bromo-2-keto-indol-3-yl)-2-pyrrol-1-yl-benzohydrazide | N'-(5-bromo-2-oxo-3-indolyl)-2-(1-pyrrolyl)benzohydrazide | N'-(5-bromo-2-oxoindol-3-yl)-2-pyrrol-1-ylbenzohydrazide | SMR000152637 | cid_6006008
Type:
Small organic molecule
Emp. Form.:
C19H13BrN4O2
Mol. Mass.:
409.236
SMILES:
Brc1ccc2=NC(=O)C(NNC(=O)c3ccccc3-n3cccc3)=c2c1 |c:25,t:4|
Structure:
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