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Target
E3 ubiquitin-protein ligase XIAP
Ligand
BDBM43781
Substrate
n/a
Meas. Tech.
Chemical Antagonists of IAP-family anti-apoptotic proteins confirmation
IC50
>200000±0 nM
Citation
 PubChem, PC Chemical Antagonists of IAP-family anti-apoptotic proteins confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
E3 ubiquitin-protein ligase XIAP
Synonyms:
API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP | IAP3 | Inhibitor of apoptosis protein 3 | Inhibitor of apoptosis protein 3 (XIAP) | X-linked inhibitor of apoptosis | X-linked inhibitor of apoptosis protein (XIAP) | XIAP | XIAP_HUMAN
Type:
Protein
Mol. Mass.:
56685.27
Organism:
Homo sapiens (Human)
Description:
P98170
Residue:
497
Sequence:
MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS
  
Inhibitor
Name:
BDBM43781
Synonyms:
2-(4-fluorophenyl)-2-(1-ketoisoindolin-2-yl)acetic acid | 2-(4-fluorophenyl)-2-(3-oxidanylidene-1H-isoindol-2-yl)ethanoic acid | 2-(4-fluorophenyl)-2-(3-oxo-1H-isoindol-2-yl)acetic acid | MLS-0315755.0001 | cid_20855134
Type:
Small organic molecule
Emp. Form.:
C16H12FNO3
Mol. Mass.:
285.2698
SMILES:
OC(=O)C(N1Cc2ccccc2C1=O)c1ccc(F)cc1
Structure:
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