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Target
Alkaline phosphatase, tissue-nonspecific isozyme
Ligand
BDBM44404
Substrate
n/a
Meas. Tech.
TNAP luminescent HTS assay
IC50
>100000±0 nM
Citation
 PubChem, PC TNAP luminescent HTS assay PubChem Bioassay (2008)[AID] 
Target
Name:
Alkaline phosphatase, tissue-nonspecific isozyme
Synonyms:
ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor
Type:
PROTEIN
Mol. Mass.:
57306.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448917
Residue:
524
Sequence:
MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
  
Inhibitor
Name:
BDBM44404
Synonyms:
MLS000090420 | SMR000025030 | [5-(hydroxymethyl)-1-[3-(trifluoromethyl)phenyl]-1,2,3-triazol-4-yl]methanol | [5-(hydroxymethyl)-1-[3-(trifluoromethyl)phenyl]-4-triazolyl]methanol | [5-(hydroxymethyl)-1-[3-(trifluoromethyl)phenyl]triazol-4-yl]methanol | [5-methylol-1-[3-(trifluoromethyl)phenyl]triazol-4-yl]methanol | cid_715064 | {4-(hydroxymethyl)-1-[3-(trifluoromethyl)phenyl]-1H-1,2,3-triazol-5-yl}methanol
Type:
Small organic molecule
Emp. Form.:
C11H10F3N3O2
Mol. Mass.:
273.2112
SMILES:
OCc1nnn(c1CO)-c1cccc(c1)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: