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Target
Alkaline phosphatase, tissue-nonspecific isozyme
Ligand
BDBM32272
Substrate
n/a
Meas. Tech.
TNAP luminescent HTS assay
IC50
>100000±0 nM
Citation
 PubChem, PC TNAP luminescent HTS assay PubChem Bioassay (2008)[AID] 
Target
Name:
Alkaline phosphatase, tissue-nonspecific isozyme
Synonyms:
ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor
Type:
PROTEIN
Mol. Mass.:
57306.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448917
Residue:
524
Sequence:
MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
  
Inhibitor
Name:
BDBM32272
Synonyms:
MLS000119995 | N-butyl-2,3-bis(2-furanyl)-6-quinoxalinecarboxamide | N-butyl-2,3-bis(2-furyl)quinoxaline-6-carboxamide | N-butyl-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide | SMR000096912 | cid_5076890
Type:
Small organic molecule
Emp. Form.:
C21H19N3O3
Mol. Mass.:
361.3939
SMILES:
CCCCNC(=O)c1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1
Structure:
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