Reaction Details Report a problem with these data
Target
Estrogen receptor beta
Ligand
BDBM42023
Substrate
n/a
Meas. Tech.
Estrogen Receptor (beta) binding: Dose Response of Primary Screen Assay
EC50
0.87±n/a nM
Citation
 PubChem, PC Estrogen Receptor (beta) binding: Dose Response of Primary Screen Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM42023
Synonyms:
2,3-di-2-furyl-6-{[4-(2-methoxyphenyl)piperazin-1-yl]carbonyl}quinoxaline | MLS000094620 | SMR000030173 | [2,3-bis(2-furanyl)-6-quinoxalinyl]-[4-(2-methoxyphenyl)-1-piperazinyl]methanone | [2,3-bis(2-furyl)quinoxalin-6-yl]-[4-(2-methoxyphenyl)piperazino]methanone | [2,3-bis(furan-2-yl)quinoxalin-6-yl]-[4-(2-methoxyphenyl)piperazin-1-yl]methanone | cid_3240449
Type:
Small organic molecule
Emp. Form.:
C28H24N4O4
Mol. Mass.:
480.5146
SMILES:
COc1ccccc1N1CCN(CC1)C(=O)c1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: