Reaction Details Report a problem with these data
Target
Estrogen receptor beta
Ligand
BDBM46293
Substrate
n/a
Meas. Tech.
Estrogen Receptor (beta) binding: Dose Response of Primary Screen Assay
EC50
39.88±n/a nM
Citation
 PubChem, PC Estrogen Receptor (beta) binding: Dose Response of Primary Screen Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM46293
Synonyms:
2-[[3-(4-ethylphenyl)-1-phenyl-pyrazol-4-yl]methyl]isothiourea;hydrochloride | MLS000681140 | SMR000269408 | [3-(4-ethylphenyl)-1-phenyl-1H-pyrazol-4-yl]methyl imidothiocarbamate hydrochloride | [3-(4-ethylphenyl)-1-phenyl-pyrazol-4-yl]methyl carbamimidothioate;hydrochloride | [3-(4-ethylphenyl)-1-phenylpyrazol-4-yl]methyl carbamimidothioate;hydrochloride | carbamimidothioic acid [3-(4-ethylphenyl)-1-phenyl-4-pyrazolyl]methyl ester;hydrochloride | cid_2901146
Type:
Small organic molecule
Emp. Form.:
C19H20N4S
Mol. Mass.:
336.454
SMILES:
CCc1ccc(cc1)-c1nn(cc1CSC(N)=N)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: