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Target
Bcl-2-like protein 10 [11-204]
Ligand
BDBM32262
Substrate
n/a
Meas. Tech.
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein.
EC50
30660±n/a nM
Citation
 PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 10 [11-204]
Synonyms:
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21981.77
Organism:
Homo sapiens (Human)
Description:
gi_23396469
Residue:
194
Sequence:
MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL
  
Inhibitor
Name:
BDBM32262
Synonyms:
5-benzyl-8-methyl-3-(methylthio)-[1,2,4]triazin[5,6-b]indole | 5-benzyl-8-methyl-3-methylsulfanyl-[1,2,4]triazino[5,6-b]indole | 8-methyl-3-(methylthio)-5-(phenylmethyl)-[1,2,4]triazino[5,6-b]indole | 8-methyl-3-methylsulfanyl-5-(phenylmethyl)-[1,2,4]triazino[5,6-b]indole | MLS000042505 | SMR000046397 | cid_6400963
Type:
Small organic molecule
Emp. Form.:
C18H16N4S
Mol. Mass.:
320.411
SMILES:
CSc1nnc2c3cc(C)ccc3n(Cc3ccccc3)c2n1
Structure:
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