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Target
Bcl-2-like protein 10 [11-204]
Ligand
BDBM32264
Substrate
n/a
Meas. Tech.
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein.
EC50
16700±n/a nM
Citation
 PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 10 [11-204]
Synonyms:
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21981.77
Organism:
Homo sapiens (Human)
Description:
gi_23396469
Residue:
194
Sequence:
MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL
  
Inhibitor
Name:
BDBM32264
Synonyms:
4-(1-azepanyl)-2-(2-pyridinyl)quinazoline | 4-(azepan-1-yl)-2-(2-pyridyl)quinazoline | 4-(azepan-1-yl)-2-pyridin-2-yl-quinazoline | 4-(azepan-1-yl)-2-pyridin-2-ylquinazoline | MLS000042263 | SMR000046752 | cid_665597
Type:
Small organic molecule
Emp. Form.:
C19H20N4
Mol. Mass.:
304.3889
SMILES:
C1CCCN(CC1)c1nc(nc2ccccc12)-c1ccccn1
Structure:
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