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Target
Bcl-2-like protein 10 [11-204]
Ligand
BDBM31703
Substrate
n/a
Meas. Tech.
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein.
EC50
49460±n/a nM
Citation
 PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 10 [11-204]
Synonyms:
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21981.77
Organism:
Homo sapiens (Human)
Description:
gi_23396469
Residue:
194
Sequence:
MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL
  
Inhibitor
Name:
BDBM31703
Synonyms:
3-(2,5-dimethyl-1-pyrrolyl)benzoic acid | 3-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid | 3-(2,5-dimethylpyrrol-1-yl)benzoic acid | MLS000053036 | SMR000068999 | cid_213329
Type:
Small organic molecule
Emp. Form.:
C13H13NO2
Mol. Mass.:
215.2478
SMILES:
Cc1ccc(C)n1-c1cccc(c1)C(O)=O
Structure:
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