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Target
Bcl-2-like protein 10 [11-204]
Ligand
BDBM32286
Substrate
n/a
Meas. Tech.
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein.
EC50
11190±n/a nM
Citation
 PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 10 [11-204]
Synonyms:
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21981.77
Organism:
Homo sapiens (Human)
Description:
gi_23396469
Residue:
194
Sequence:
MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL
  
Inhibitor
Name:
BDBM32286
Synonyms:
4-(4-carbomethoxyanilino)quinazoline-2-carboxylic acid ethyl ester | 4-(4-methoxycarbonylanilino)-2-quinazolinecarboxylic acid ethyl ester | MLS000519323 | SMR000129742 | cid_1192536 | ethyl 4-(4-methoxycarbonylanilino)quinazoline-2-carboxylate | ethyl 4-[(4-methoxycarbonylphenyl)amino]quinazoline-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C19H17N3O4
Mol. Mass.:
351.356
SMILES:
CCOC(=O)c1nc(Nc2ccc(cc2)C(=O)OC)c2ccccc2n1
Structure:
Search PDB for entries with ligand similarity: