Reaction Details Report a problem with these data
Target
Bcl-2-like protein 10 [11-204]
Ligand
BDBM32302
Substrate
n/a
Meas. Tech.
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein.
EC50
35710±n/a nM
Citation
 PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 10 [11-204]
Synonyms:
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21981.77
Organism:
Homo sapiens (Human)
Description:
gi_23396469
Residue:
194
Sequence:
MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL
  
Inhibitor
Name:
BDBM32302
Synonyms:
1H-benzimidazol-2-yl-[(2-chloro-3-quinolyl)methyleneamino]amine | MLS000332154 | N-(1H-Benzoimidazol-2-yl)-N'-[1-(2-chloro-quinolin-3-yl)-meth-(E)-ylidene]-hydrazine | N-[(2-chloranylquinolin-3-yl)methylideneamino]-1H-benzimidazol-2-amine | N-[(2-chloro-3-quinolinyl)methylideneamino]-1H-benzimidazol-2-amine | N-[(2-chloroquinolin-3-yl)methylideneamino]-1H-benzimidazol-2-amine | SMR000221568 | cid_3842853
Type:
Small organic molecule
Emp. Form.:
C17H12ClN5
Mol. Mass.:
321.764
SMILES:
Clc1nc2ccccc2cc1CN=Nc1nc2ccccc2[nH]1 |w:13.15|
Structure:
Search PDB for entries with ligand similarity: