Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM46321
Substrate
n/a
Meas. Tech.
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype
EC50
3028±n/a nM
Citation
 PubChem, PC Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM46321
Synonyms:
(2E)-5-bromo-4-chloro-2-{[(3,5-dimethylphenyl)amino]methylene}-1,2-dihydro-3H-indol-3-one | (2Z)-5-bromanyl-4-chloranyl-2-[[(3,5-dimethylphenyl)amino]methylidene]-1H-indol-3-one | (2Z)-5-bromo-4-chloro-2-[(3,5-dimethylanilino)methylene]pseudoindoxyl | (2Z)-5-bromo-4-chloro-2-[(3,5-dimethylanilino)methylidene]-1H-indol-3-one | MLS000586008 | SMR000207787 | cid_12004427
Type:
Small organic molecule
Emp. Form.:
C17H14BrClN2O
Mol. Mass.:
377.663
SMILES:
Cc1cc(C)cc(c1)N=Cc1[nH]c2ccc(Br)c(Cl)c2c1O |w:8.8|
Structure:
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