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Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM46322
Substrate
n/a
Meas. Tech.
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype
EC50
634.2±n/a nM
Citation
 PubChem, PC Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM46322
Synonyms:
(4E)-2-methoxy-4-[(5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazo)methylidene]-1-cyclohexa-2,5-dienone | (4E)-2-methoxy-4-[[2-(5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazinyl]methylidene]cyclohexa-2,5-dien-1-one | (4E)-2-methoxy-4-[[N'-(5H-[1,2,4]triazin[5,6-b]indol-3-yl)hydrazino]methylene]cyclohexa-2,5-dien-1-one | 2-Methoxy-4-[(9H-1,3,4,9-tetraaza-fluoren-2-yl)-hydrazonomethyl]-phenol | MLS000554463 | SMR000171289 | cid_5722242
Type:
Small organic molecule
Emp. Form.:
C17H14N6O2
Mol. Mass.:
334.3321
SMILES:
COc1cc(CN=Nc2nnc3c(n2)[nH]c2ccccc32)ccc1O |w:7.7|
Structure:
Search PDB for entries with ligand similarity: