Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM46323
Substrate
n/a
Meas. Tech.
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype
EC50
3456±n/a nM
Citation
 PubChem, PC Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM46323
Synonyms:
1-[(5-fluoranyl-2-oxidanylidene-indol-3-yl)amino]thiourea | MLS000553762 | SMR000171277 | [(5-fluoro-2-keto-indol-3-yl)amino]thiourea | [(5-fluoro-2-oxo-3-indolyl)amino]thiourea | [(5-fluoro-2-oxoindol-3-yl)amino]thiourea | cid_5295055
Type:
Small organic molecule
Emp. Form.:
C9H7FN4OS
Mol. Mass.:
238.241
SMILES:
NC(=S)NNC1=c2cc(F)ccc2=NC1=O |c:5,13|
Structure:
Search PDB for entries with ligand similarity: