Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM46329
Substrate
n/a
Meas. Tech.
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype
EC50
20760±n/a nM
Citation
 PubChem, PC Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM46329
Synonyms:
1,3-dimethyl-2-oxidanylidene-perimidine-6-carbaldehyde | 1,3-dimethyl-2-oxo-2,3-dihydro-1H-perimidine-6-carbaldehyde | 1,3-dimethyl-2-oxo-6-perimidinecarboxaldehyde | 1,3-dimethyl-2-oxoperimidine-6-carbaldehyde | 2-keto-1,3-dimethyl-perimidine-6-carbaldehyde | MLS000624980 | SMR000293751 | cid_919421
Type:
Small organic molecule
Emp. Form.:
C14H12N2O2
Mol. Mass.:
240.2573
SMILES:
Cn1c2cccc3c(C=O)ccc(n(C)c1=O)c23
Structure:
Search PDB for entries with ligand similarity: