Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM46330
Substrate
n/a
Meas. Tech.
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype
EC50
5412±n/a nM
Citation
 PubChem, PC Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM46330
Synonyms:
MLS000335629 | N-[2-(4-chlorophenyl)ethyl]-2-(7-nitroquinazolin-4-yl)oxy-acetamide | N-[2-(4-chlorophenyl)ethyl]-2-(7-nitroquinazolin-4-yl)oxy-ethanamide | N-[2-(4-chlorophenyl)ethyl]-2-(7-nitroquinazolin-4-yl)oxyacetamide | N-[2-(4-chlorophenyl)ethyl]-2-[(7-nitro-4-quinazolinyl)oxy]acetamide | SMR000253383 | cid_4264326
Type:
Small organic molecule
Emp. Form.:
C18H15ClN4O4
Mol. Mass.:
386.789
SMILES:
[O-][N+](=O)c1ccc2c(OCC(=O)NCCc3ccc(Cl)cc3)ncnc2c1
Structure:
Search PDB for entries with ligand similarity: