Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43234
Substrate
n/a
Meas. Tech.
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype
EC50
19020±n/a nM
Citation
 PubChem, PC Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43234
Synonyms:
2-[(4-chloranylphenoxy)methyl]-5-methoxy-1-benzofuran-3-carboxylic acid | 2-[(4-chlorophenoxy)methyl]-5-methoxy-1-benzofuran-3-carboxylic acid | 2-[(4-chlorophenoxy)methyl]-5-methoxy-3-benzofurancarboxylic acid | 2-[(4-chlorophenoxy)methyl]-5-methoxy-benzofuran-3-carboxylic acid | UNM000011078301 | cid_1502918
Type:
Small organic molecule
Emp. Form.:
C17H13ClO5
Mol. Mass.:
332.735
SMILES:
COc1ccc2oc(COc3ccc(Cl)cc3)c(C(O)=O)c2c1
Structure:
Search PDB for entries with ligand similarity: