Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43283
Substrate
n/a
Meas. Tech.
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype
EC50
16040±n/a nM
Citation
 PubChem, PC Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43283
Synonyms:
4-methyl-5-(o-anisidinomethyl)-2-thenoic acid | 5-[(2-methoxyanilino)methyl]-4-methyl-2-thiophenecarboxylic acid | 5-[(2-methoxyanilino)methyl]-4-methylthiophene-2-carboxylic acid | 5-[[(2-methoxyphenyl)amino]methyl]-4-methyl-thiophene-2-carboxylic acid | UNM000011082001 | cid_20899537
Type:
Small organic molecule
Emp. Form.:
C14H15NO3S
Mol. Mass.:
277.339
SMILES:
COc1ccccc1NCc1sc(cc1C)C(O)=O
Structure:
Search PDB for entries with ligand similarity: