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Target
Mannose-6-phosphate isomerase
Ligand
BDBM46620
Substrate
n/a
Meas. Tech.
Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay.
IC50
33800±n/a nM
Citation
 PubChem, PC Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay (2010)[AID] 
Target
Name:
Mannose-6-phosphate isomerase
Synonyms:
MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1
Type:
PROTEIN
Mol. Mass.:
46651.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448919
Residue:
423
Sequence:
MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLKQTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQLHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYKVLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRACCLL
  
Inhibitor
Name:
BDBM46620
Synonyms:
6-fluoranyl-2-(4-methoxyphenyl)-1,2-benzothiazol-3-one | 6-fluoro-2-(4-methoxyphenyl)-1,2-benzothiazol-3-one | MLS-0315772.0001 | cid_1519965
Type:
Small organic molecule
Emp. Form.:
C14H10FNO2S
Mol. Mass.:
275.298
SMILES:
COc1ccc(cc1)-n1sc2cc(F)ccc2c1=O
Structure:
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