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Target
Mannose-6-phosphate isomerase
Ligand
BDBM46679
Substrate
n/a
Meas. Tech.
Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay.
IC50
4350±n/a nM
Citation
 PubChem, PC Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay (2010)[AID] 
Target
Name:
Mannose-6-phosphate isomerase
Synonyms:
MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1
Type:
PROTEIN
Mol. Mass.:
46651.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448919
Residue:
423
Sequence:
MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLKQTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQLHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYKVLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRACCLL
  
Inhibitor
Name:
BDBM46679
Synonyms:
(4-chlorodithiazol-5-ylidene)-(2,5-dimethoxyphenyl)amine | 4-chloranyl-N-(2,5-dimethoxyphenyl)-1,2,3-dithiazol-5-imine | 4-chloro-N-(2,5-dimethoxyphenyl)-5-dithiazolimine | 4-chloro-N-(2,5-dimethoxyphenyl)dithiazol-5-imine | MLS-0390822.0001 | cid_483894
Type:
Small organic molecule
Emp. Form.:
C10H9ClN2O2S2
Mol. Mass.:
288.774
SMILES:
COc1ccc(OC)c(c1)\N=c1\ssnc1Cl
Structure:
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