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Target
Procathepsin L
Ligand
BDBM30875
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response testing in the presence of cysteine
IC50
920.07±133.361321 nM
Citation
 PubChem, PC Cathepsin L dose-response testing in the presence of cysteine PubChem Bioassay (2009)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM30875
Synonyms:
MLS000043125 | N-(4-{[(2Z)-2-({[4-(acetylamino)phenyl]sulfonyl}imino)-1,3-thiazolidin-3-yl]sulfonyl}phenyl)acetamide | N-[4-[[3-(4-acetamidophenyl)sulfonyl-1,3-thiazolidin-2-ylidene]amino]sulfonylphenyl]acetamide | N-[4-[[3-(4-acetamidophenyl)sulfonyl-1,3-thiazolidin-2-ylidene]amino]sulfonylphenyl]ethanamide | N-[4-[[3-(4-acetamidophenyl)sulfonyl-2-thiazolidinylidene]amino]sulfonylphenyl]acetamide | N-[4-[[3-(4-acetamidophenyl)sulfonylthiazolidin-2-ylidene]amino]sulfonylphenyl]acetamide | SMR000019552 | cid_3241855
Type:
Small organic molecule
Emp. Form.:
C19H20N4O6S3
Mol. Mass.:
496.58
SMILES:
CC(=O)Nc1ccc(cc1)S(=O)(=O)N=C1SCCN1S(=O)(=O)c1ccc(NC(C)=O)cc1 |w:13.13|
Structure:
Search PDB for entries with ligand similarity: