Reaction Details Report a problem with these data
Target
Procathepsin L
Ligand
BDBM41368
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response testing in the presence of cysteine
IC50
>46492.615±3507.385 nM
Citation
 PubChem, PC Cathepsin L dose-response testing in the presence of cysteine PubChem Bioassay (2009)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41368
Synonyms:
1,5-dimethyl-4-oxidanylidene-N-[2-[4-(phenylmethyl)piperazin-1-yl]ethyl]pyrrolo[3,2-c]quinoline-2-carboxamide | 1,5-dimethyl-4-oxo-N-[2-[4-(phenylmethyl)-1-piperazinyl]ethyl]-2-pyrrolo[3,2-c]quinolinecarboxamide | MLS000118133 | N-[2-(4-benzylpiperazin-1-yl)ethyl]-1,5-dimethyl-4-oxopyrrolo[3,2-c]quinoline-2-carboxamide | N-[2-(4-benzylpiperazino)ethyl]-4-keto-1,5-dimethyl-pyrrolo[3,2-c]quinoline-2-carboxamide | SMR000095081 | cid_5308662
Type:
Small organic molecule
Emp. Form.:
C27H31N5O2
Mol. Mass.:
457.5673
SMILES:
Cn1c(cc2c1c1ccccc1n(C)c2=O)C(=O)NCCN1CCN(Cc2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: