Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM47031
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM47031
Synonyms:
3-[(4-chloranyl-1,2,3-dithiazol-5-ylidene)amino]-N,N-dimethyl-aniline | 3-[(4-chloro-5-dithiazolylidene)amino]-N,N-dimethylaniline | 3-[(4-chlorodithiazol-5-ylidene)amino]-N,N-dimethylaniline | MLS-0390891.0001 | [3-[(4-chlorodithiazol-5-ylidene)amino]phenyl]-dimethyl-amine | cid_25181213
Type:
Small organic molecule
Emp. Form.:
C10H10ClN3S2
Mol. Mass.:
271.79
SMILES:
CN(C)c1cccc(c1)\N=c1/ssnc1Cl
Structure:
Search PDB for entries with ligand similarity: