Reaction Details Report a problem with these data
Target
Phosphoethanolamine/phosphocholine phosphatase
Ligand
BDBM47033
Substrate
n/a
Meas. Tech.
SAR assay for compounds that inhibit PHOSPHO1
IC50
4990±n/a nM
Citation
 PubChem, PC SAR assay for compounds that inhibit PHOSPHO1 PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphoethanolamine/phosphocholine phosphatase
Synonyms:
PHOP1_HUMAN | PHOSPHO1 | phosphatase, orphan 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29718.09
Organism:
Homo sapiens (Human)
Description:
Q8TCT1
Residue:
267
Sequence:
MSGCFPVSGLRCLSRDGRMAAQGAPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPESLRATYREGFYNEYMQRVFKYLGEQGVRPRDLSAIYEAIPLSPGMSDLLQFVAKQGACFEVILISDANTFGVESSLRAAGHHSLFRRILSNPSGPDARGLLALRPFHTHSCARCPANMCKHKVLSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEPSSFRASVVPWETAADVRLHLQQVLKSC
  
Inhibitor
Name:
BDBM47033
Synonyms:
(2,3-diphenyl-1,2,4-thiadiazol-2-ium-5-yl)-phenyl-amine;hydrobromide | MLS-0390885.0001 | N,2,3-triphenyl-1,2,4-thiadiazol-2-ium-5-amine;hydrobromide | cid_25181254
Type:
Small organic molecule
Emp. Form.:
C20H16N3S
Mol. Mass.:
330.426
SMILES:
N(c1nc(-c2ccccc2)[n+](s1)-c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: