Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47616
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
1398±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47616
Synonyms:
2-amino-3-[(4-hydroxyphenyl)diazenyl]-7-methylpyrazolo[1,5-a]pyrimidin-5(4H)-one | 2-amino-3-[N'-(4-ketocyclohexa-2,5-dien-1-ylidene)hydrazino]-7-methyl-1H-pyrazolo[1,5-a]pyrimidin-5-one | 2-amino-7-methyl-3-[2-(4-oxo-1-cyclohexa-2,5-dienylidene)hydrazinyl]-1H-pyrazolo[1,5-a]pyrimidin-5-one | 2-amino-7-methyl-3-[2-(4-oxocyclohexa-2,5-dien-1-ylidene)hydrazinyl]-1H-pyrazolo[1,5-a]pyrimidin-5-one | 2-azanyl-7-methyl-3-[2-(4-oxidanylidenecyclohexa-2,5-dien-1-ylidene)hydrazinyl]-1H-pyrazolo[1,5-a]pyrimidin-5-one | MLS000705177 | SMR000230990 | cid_5705988
Type:
Small organic molecule
Emp. Form.:
C13H12N6O2
Mol. Mass.:
284.2734
SMILES:
Cc1cc(=O)[nH]c2c(N=Nc3ccc(O)cc3)c(N)nn12 |w:8.7|
Structure:
Search PDB for entries with ligand similarity: