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Target
Regulator of G-protein signaling 8
Ligand
BDBM47743
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47743
Synonyms:
2-Bromo-N-[1-methyl-2-phenyl-eth-(E)-ylidene-hydrazinocarbonylmethyl]-benzamide | 2-bromanyl-N-[2-oxidanylidene-2-[2-(1-phenylpropan-2-ylidene)hydrazinyl]ethyl]benzamide | 2-bromo-N-[2-keto-2-[N'-(1-methyl-2-phenyl-ethylidene)hydrazino]ethyl]benzamide | 2-bromo-N-[2-oxo-2-[2-(1-phenylpropan-2-ylidene)hydrazinyl]ethyl]benzamide | MLS000587416 | SMR000211388 | cid_603176
Type:
Small organic molecule
Emp. Form.:
C18H18BrN3O2
Mol. Mass.:
388.258
SMILES:
CC(Cc1ccccc1)=NNC(=O)CNC(=O)c1ccccc1Br |w:9.10|
Structure:
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