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Target
Regulator of G-protein signaling 8
Ligand
BDBM47745
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47745
Synonyms:
5-([1,3]dioxolo[4,5-f][1,3]benzothiazol-6-ylamino)-3-methyl-2-thiophenecarboxylic acid ethyl ester | 5-([1,3]dioxolo[4,5-f][1,3]benzothiazol-6-ylamino)-3-methyl-thiophene-2-carboxylic acid ethyl ester | MLS000720389 | SMR000236240 | cid_7110093 | ethyl 5-([1,3]dioxolo[4,5-f][1,3]benzothiazol-6-ylamino)-3-methyl-thiophene-2-carboxylate | ethyl 5-([1,3]dioxolo[4,5-f][1,3]benzothiazol-6-ylamino)-3-methylthiophene-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C16H14N2O4S2
Mol. Mass.:
362.423
SMILES:
CCOC(=O)c1sc(Nc2nc3cc4OCOc4cc3s2)cc1C
Structure:
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